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CRISPR multi-screen integration to prioritize multi-phenotype targets

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TargetPP

DOI

CRISPR multi-screen integration to prioritize multi-phenotype targets

This target prioritization pipeline (TPP, TargetPP) combines existing statistical methods to integrate multiple CRISPR screens into a single ranking to prioritize targets based on their significance and effect size, even across multiple phenotypes.

Installation

You can install the released version of TargetPP by running:

install.packages("devtools")
devtools::install_github("RescueGum/TargetPP")

Example

This is a basic example which shows you how to solve a common problem:

library(TargetPP)
## TODO: basic example code

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