CRISPR multi-screen integration to prioritize multi-phenotype targets
This target prioritization pipeline (TPP, TargetPP) combines existing statistical methods to integrate multiple CRISPR screens into a single ranking to prioritize targets based on their significance and effect size, even across multiple phenotypes.
You can install the released version of TargetPP by running:
install.packages("devtools")
devtools::install_github("RescueGum/TargetPP")This is a basic example which shows you how to solve a common problem:
library(TargetPP)
## TODO: basic example code