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Simulation experiments for the TROUPE paper

This repository provides code to replicate the experiments in the paper "Inferring Cell Differentiation Dynamics with Unobserved Progenitors". Note that it assumes access to a SLURM scheduled cluster.

First clone this repository and initialize the it using

python -m venv .venv
source .venv/bin/activate
pip install -r requirements.txt

Then clone TROUPE into a separate directory with

cd ..
git clone https://github.com/raphael-group/troupe.git

and cd into troupe, install as a package, then go back to the experiments directory

cd troupe
pip install -e .
cd ../troupe_experiments

To simulate trees, run the following command:

bash scripts/simulate_trees.sh

To get results for each method run the corresponding cluster script. For example, if you want to run TROUPE, you'd write

bash scripts/troupe/run_cluster_inference.sh

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