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kakyungkim/README.md

Ka-Kyung Kim, Ph.D.

From specimen to clinical decision. I design and operate genomics analysis that ends up in reports and services a hospital actually uses, and I measure how far those results can be trusted.

Chief Researcher, Diagnosis Division, Cytogen — CTC-based liquid biopsy, Seoul, Korea.

20+ years omics and clinical data  ·  20+ peer-reviewed papers  ·  7 institutions and companies  ·  4 degrees across computer science, life science, and molecular medicine

Portfolio · Blog · CV · Google Scholar · ORCID · LinkedIn · kakyung.kim@gmail.com


Recent highlights

  • 2026.11 — Oral presentation accepted at BIOINFO 2026 / GIW XXXV / ISCB-Asia (22 of 287 submissions): a reliability map for per-gene multiome RNA velocity parameters. A second abstract from the same harness was accepted as a poster.
  • 2026 — Shipped a cell image review assistant in-house, trained on 1,531 cells drawn from reader decisions. Slide-level cross-validation had inflated agreement to kappa 0.910; re-splitting at the specimen level to block leakage brought it to 0.704, and the corrected figure is the one that shipped. Confidence-based triage cut the cells needing priority human confirmation by 70%.
  • 2026 — Published an ADMET split audit on public data. Across 12 Therapeutics Data Commons tasks, a structure-disjoint split degraded all 12 (median drop 0.098); on screening metrics, top-10% hit rate fell on all 8 tasks tested and VDss went from 0.358 to 0.176 (p<0.001). Raising seeds from 5 to 15 narrowed the gaps enough to retract three of my own initial conclusions, and I published the correction. Write-up (Korean)
  • 2026 — Fifth trend report in BRIC View (2026-T24, generative AI in biotech and drug discovery).
  • Since 2026.06 — Two agent harnesses running in the open: econ-radar daily, paper-radar weekly.

Selected publications

Year Work Venue Role
2019 Whole-exome and whole-transcriptome sequencing of canine mammary gland tumors Scientific Data 6(1):147 First author
2013 miRTCat: a comprehensive map of human and mouse microRNA target sites Bioinformatics 29(15):1898 First author
2018 Palmitate and mmLDL cooperatively promote inflammatory responses in macrophages PLoS One 13:e0193649 Co-first author
2020 Cross-species oncogenic signatures of breast cancer in canine mammary tumors Nature Communications 11:3616 Co-author
2022 GWAS identifies TNFSF15 associated with childhood asthma Allergy 77(1):218 Co-author
2021 Genetic features of gastric mixed adenoneuroendocrine carcinomas Journal of Pathology 253(1):94 Co-author

Full list on Google Scholar, ORCID, and the portfolio. Three manuscripts in preparation.

What I build

Automate the interpretation, but leave the evidence so a person can check it.

Repository What it does
econ-radar Agent harness publishing a daily economic digest weighted toward pharma, bio, and AI. Collection, selection, summarization, and publishing split across agents. Daily brief plus weekly roundup, running since June 2026.
paper-radar Weekly digest of bioinformatics, clinical ML, and drug-discovery AI papers, sorted into three readings: method, clinic, and industry.
paper-production-harness Topic-agnostic multi-agent harness that runs a paper from analysis through to the talk. CC BY 4.0.
korea-agentic-hackathon-2026 Drug candidate validation agent that catches claims a docking score cannot support. NVIDIA × FastCampus Korea Agentic AI Hackathon 2026.
pharmasignal-v0 Drug safety signal agent over regulatory filings and trial registries. Inference is routed by data sensitivity, so restricted material never reaches a commercial API. Agent Forge AI Hackathon Seoul 2026.
chillmcp MCP server built with FastMCP: 12 model-callable tools and 5 interactive prompts, MIT licensed. SKT AI Summit Hackathon 2025.

Closed-source work includes VeriVar, a dual-mode somatic variant interpretation pipeline where an LLM mode and a rule-based mode run side by side and their disagreements serve as a verification signal, and AutoBioX, the multi-agent research harness behind the GIW 2026 abstracts.

Talks and writing

  • BIOINFO 2026 / GIW XXXV / ISCB-Asia — oral presentation, accepted 22 of 287 (Nov 2026, upcoming)
  • PseudoCon 2026 — the AutoBioX multi-agent pipeline
  • ABDD Summit 2026, Stanford — automated clinical reporting for oncology NGS: a dual-mode LLM pipeline (i-Talk and poster)
  • Future of Medicine Symposium 2025 — single-cell QC standardization and an scRNA-seq × immunofluorescence pipeline (lightning talk)
  • BRIC View — five invited trend reports (2017, 2018, 2025, 2026 ×2) on cloud genomics, allergy therapeutics, single-cell in drug discovery, bio big data, and generative AI

I write up what I built and where I went wrong, in Korean and English: kakyungkim.github.io.

Awards

Korea Clinical Datathon, Grand Prize (2019, sepsis prediction, KoNECT) · Cheiron ResearchThon, Creative Academic Impact Award (2025) · ABDD Summit, Best Poster (2024) · KSMCB Annual Meeting, Outstanding Poster (2011)

Stack

  • Omics — multi-platform NGS (WES, WGS, RNA-seq, scRNA-seq, multiome, liquid biopsy), Nextflow, Seurat/Scanpy, AWS
  • AI — PyTorch, pathology foundation model embeddings, LLM agent harnesses, RAG with citation grounding, MCP
  • Clinical — Ph1–3 trial analysis, clinical report automation, GCLP/CAP/ISO quality systems
  • Languages — Python, R, Bash, SQL

Education

Ph.D. Molecular Medicine, Sungkyunkwan University (2011)  ·  M.S. Life Science, Korea University (2004)  ·  B.S. Computer Science, Dongguk University (2000)  ·  B.S. Health & Environment and Business, Korea National Open University (2023)

Popular repositories Loading

  1. korea-agentic-hackathon-2026 korea-agentic-hackathon-2026 Public

    도킹 점수에서 나올 수 없는 주장을 잡는 신약 후보 검증 에이전트. NVIDIA x 패스트캠퍼스 Korea Agentic AI Hackathon 2026

    Python 1 1

  2. kakyungkim kakyungkim Public

    Config files for my GitHub profile.

  3. first-repository first-repository Public

    Jupyter Notebook

  4. first-fork first-fork Public

    Forked from ez4happy/first-repository

    Jupyter Notebook

  5. aiffel aiffel Public

    Jupyter Notebook

  6. kakyungkim_portfolio kakyungkim_portfolio Public

    Forked from dongchanlim/portfolio_template

    This is Ka-Kyung Kim's portfolio