GP2 ❤️ Open Science 😍
Last updated: July 2026
This is the online repository for the manuscript titled "The Progressive Supranuclear Palsy Clinical Deficits Scale (PSP-CDS) tracks longitudinal progression in PSP". This study focuses on assessing the ability of PSP-CDS to track disease progression over time and comparing progression across PSP phenotypes in a real-world Asian cohort.
Data used in the preparation of this article were contributed to the Global Parkinson’s Genetics Program (GP2). Specifically, we will share Tier 2 data in GP2 Release 13 (see current releases at https://zenodo.org/records/20932193). GP2 is funded by the Aligning Science Across Parkinson’s (ASAP) initiative and implemented by The Michael J. Fox Foundation for Parkinson’s Research (gp2.org). For a complete list of GP2 members see gp2.org.
All GP2 data are hosted in collaboration with the Accelerating Medicines Partnership in Parkinson’s disease, and are available via application on the website (https://amp-pd.org/register-for-amp-pd). For up-to-date information on GP2 data acquisition, access, and policies, visit https://gp2.org/. Tier 1 data can be accessed by completing a form on the Accelerating Medicines Partnership in Parkinson’s Disease (AMP®-PD) website (https://amp-pd.org/register-for-amp-pd). Tier 2 data access requires approval and a Data Use Agreement signed by your institution.
- The
analyses/directory contains the R script used for all analyses presented in the manuscript.
THIS_REPO/
├── analyses/
│ └── UM_PSP-CDS_Script.R
├── LICENSE
└── README.md
| Directory | Notebooks | Description |
|---|---|---|
analyses/ |
UM_PSP-CDS_Script.R |
R Script for reproducing all analyses included in the manuscript |
| Software | Version(s) | Resource URL | RRID | Notes |
|---|---|---|---|---|
| R Project for Statistical Computing | v.4.6.0 | https://www.r-project.org | RRID:SCR_001905 | Used for general data wrangling, statistical analyses and visualization. Key packages include tidyverse, lme4, lmerTest, ggplot2, pwr, fmsb, and lubridate. |