diff --git a/packages/react-native-executorch/android/CMakeLists.txt b/packages/react-native-executorch/android/CMakeLists.txt
index 433e4523d6..0212e869f8 100644
--- a/packages/react-native-executorch/android/CMakeLists.txt
+++ b/packages/react-native-executorch/android/CMakeLists.txt
@@ -45,7 +45,6 @@ endif()
 add_library(${CMAKE_PROJECT_NAME} SHARED ${RNE_SOURCES})
 
 target_compile_definitions(${CMAKE_PROJECT_NAME} PRIVATE
-    C10_USING_CUSTOM_GENERATED_MACROS=1
     EXECUTORCH_ENABLE_EXECUTION_PROFILING=1
 )
 
diff --git a/packages/react-native-executorch/compile_flags.txt b/packages/react-native-executorch/compile_flags.txt
index 5e215eaad2..2c10ab04f7 100644
--- a/packages/react-native-executorch/compile_flags.txt
+++ b/packages/react-native-executorch/compile_flags.txt
@@ -1,6 +1,5 @@
 -xc++
 -std=c++20
--DC10_USING_CUSTOM_GENERATED_MACROS=1
 -DEXECUTORCH_ENABLE_EXECUTION_PROFILING=1
 -Icpp
 -isystem../../node_modules/react-native/ReactCommon/jsi
diff --git a/packages/react-native-executorch/react-native-executorch.podspec b/packages/react-native-executorch/react-native-executorch.podspec
index 3f2ef08540..2d091e33d8 100644
--- a/packages/react-native-executorch/react-native-executorch.podspec
+++ b/packages/react-native-executorch/react-native-executorch.podspec
@@ -116,7 +116,6 @@ Pod::Spec.new do |s|
     "OTHER_CPLUSPLUSFLAGS" => extra_compiler_flags.join(' '),
     "GCC_PREPROCESSOR_DEFINITIONS" => [
       "$(inherited)",
-      "C10_USING_CUSTOM_GENERATED_MACROS=1",
       "EXECUTORCH_ENABLE_EXECUTION_PROFILING=1",
     ].join(' '),
     "HEADER_SEARCH_PATHS" => [