diff --git a/src/ontology/uberon-edit.obo b/src/ontology/uberon-edit.obo
index 8b8bae947..2ccffb11a 100644
--- a/src/ontology/uberon-edit.obo
+++ b/src/ontology/uberon-edit.obo
@@ -189951,6 +189951,39 @@ property_value: dcterms-date "2026-06-03T00:00:00Z" xsd:dateTime
 property_value: term_tracker_item "https://github.com/obophenotype/uberon/issues/3729" xsd:anyURI
 created_by: dragon-ai-agent
 
+[Term]
+id: UBERON:1200342
+name: bone marrow of skull
+def: "A bone marrow that is located within the bones of the skull. In mammals, skull bone marrow is haematopoietically active and communicates directly with the dura mater through osseous skull channels, which permit the exchange of cerebrospinal fluid, central nervous system-derived antigens and immune cells; it acts as a local reservoir of myeloid cells and B cells for the meninges and the central nervous system." [PMID:30150661, PMID:34083447, PMID:35301477, PMID:37996526, PMID:42618784]
+comment: Distinguished from other bone marrow sites (for example sternal, femoral, tibial or vertebral marrow) by its direct osseous connection to the dura mater. Reported to contain lymphoid structures with germinal-centre-like features that respond to central nervous system-derived antigens (PMID:42618784).
+synonym: "cranial bone marrow" RELATED []
+synonym: "skull BM" RELATED OMO:0003000 []
+synonym: "skull bone marrow" EXACT []
+xref: SCTID:712962003
+intersection_of: UBERON:0002371 ! bone marrow
+intersection_of: part_of UBERON:0003129 ! skull
+relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 ! Christopher J. Mungall
+property_value: dcterms-date "2026-08-20T04:59:35Z" xsd:dateTime
+property_value: external_ontology_notes "SCTID:712962003 ('Structure of bone marrow of cranium') is scoped to the cranium rather than the whole skull, so it excludes mandibular marrow that this class admits; its SNOMED children cover frontal, temporal, sphenoid and nasal-orbit marrow. The FMA has no corresponding grouping class - it descends from 'Bone marrow of flat bone' (FMA:303320) straight to per-bone classes such as FMA:303380 (frontal), FMA:303382 (parietal), FMA:303388 (occipital) and FMA:303454 (temporal) - so no FMA xref is asserted here." xsd:string {external_ontology="FMA"}
+property_value: term_tracker_item "https://github.com/obophenotype/uberon/pull/3758" xsd:anyURI
+property_value: terminology_notes "In the neuroimmunology literature 'skull bone marrow' is generally used for calvarial marrow specifically (see 'bone marrow of calvaria'); marrow of the basicranium (UBERON:0002517) is sampled and reported as a separate compartment, as are vertebral, sternal and femoral marrow. Annotate to 'bone marrow of calvaria' where the calvaria is what was sampled." xsd:string
+
+[Term]
+id: UBERON:1200343
+name: bone marrow of calvaria
+def: "A bone marrow of skull that is located within the diploic spaces of the calvaria (skull vault). It is the principal haematopoietic compartment of the mammalian skull and is connected to the dura mater by transcalvarial channels; its immune composition differs between anterior (frontal, parietal) and posterior (interparietal, occipital) territories." [PMID:35301477, PMID:41389063, PMID:42618784]
+comment: In the mouse, lymphoid clusters containing follicular helper-like T cells, B cells and follicular dendritic cells are enriched in the marrow of the occipital and interparietal regions and are sparse in the frontal and parietal regions (PMID:42618784).
+synonym: "calvarial bone marrow" EXACT []
+synonym: "calvarial marrow" EXACT []
+synonym: "skull cap bone marrow" RELATED []
+intersection_of: UBERON:1200342 ! bone marrow of skull
+intersection_of: part_of UBERON:0004339 ! vault of skull
+relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 ! Christopher J. Mungall
+property_value: dcterms-date "2026-08-20T04:59:35Z" xsd:dateTime
+property_value: external_ontology_notes "Neither the FMA nor SNOMED has a calvarial marrow grouping class. The FMA covers the same territory with per-bone classes: FMA:303380 (frontal), FMA:303382 (parietal), FMA:303388 (occipital) and FMA:303390 (sutural bone); these are the natural xref targets if regional calvarial marrow terms are added." xsd:string {external_ontology="FMA"}
+property_value: term_tracker_item "https://github.com/obophenotype/uberon/pull/3758" xsd:anyURI
+property_value: terminology_notes "The differentia uses 'vault of skull' (UBERON:0004339), whose own comment records that the vault may not be precisely equivalent to the calvaria - sources differ on whether the temporal, ethmoid and sphenoid bones are included. That ambiguity is inherited here rather than introduced: this class is intended as the marrow of whatever 'vault of skull' covers, which is the compartment the calvarial bone marrow literature samples." xsd:string
+
 [Term]
 id: UBERON:1500000
 name: scapular blade