iof-av:adaptedFrom should be URL not literal

[VladimirAlexiev]

You define iof-av:adaptedFrom thusly:

iof-av:adaptedFrom  rdf:type  owl:AnnotationProperty ;
        rdfs:subPropertyOf  dcterms:source ;

dct:source is merely rdf:Property but there's a skos:note "This term is intended to be used with non-literal values": that's really the difference between dct:source and dc:source
So iof-av:adaptedFrom should also point to a resource.

But then you use it as a string:

iof-core:roleOf  rdf:type   owl:ObjectProperty ;
        iof-av:adaptedFrom  "http://purl.obolibrary.org/obo/RO_0000081" ;

Please change this to a URL <http://purl.obolibrary.org/obo/RO_0000081>.

Which will have the added benefit that many tools will show it as a clickable link.

[VladimirAlexiev]

In other cases you use a literal with URI datatype:

iof-core:isOutputOf  rdf:type  owl:ObjectProperty ;
        iof-av:adaptedFrom  "http://www.ontologyrepository.com/CommonCoreOntologies/Mid/ExtendedRelationOntology"^^xsd:anyURI ;

That's a bit better, but I've asked before what's the benefit of such literal compared to a real URL.

I found only one benefit so far: if the URL is invalid, a repository will reject the URL but will happily accept the xsd:anyURI.
Which is not the case here!