diff --git a/.readthedocs.yaml b/.readthedocs.yaml
new file mode 100644
index 00000000..ff8edf65
--- /dev/null
+++ b/.readthedocs.yaml
@@ -0,0 +1,14 @@
+version: 2
+
+build:
+  os: ubuntu-24.04
+  tools:
+    python: "3.11"
+
+sphinx:
+  configuration: documentation/conf.py
+
+python:
+  install:
+    - requirements: documentation/requirements.txt
+
diff --git a/documentation/conf.py b/documentation/conf.py
new file mode 100644
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--- /dev/null
+++ b/documentation/conf.py
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+# -- Project information -----------------------------------------------------
+
+project = "TESK"
+author = "TESK contributors"
+
+# -- General configuration ---------------------------------------------------
+
+extensions = [
+    "myst_parser",
+]
+
+templates_path = ["_templates"]
+exclude_patterns = []
+
+# Markdown support
+source_suffix = {
+    ".rst": "restructuredtext",
+    ".md": "markdown",
+}
+
+# Root document (Sphinx 2.0+)
+root_doc = "index"
+
+# Backwards compatibility for older Sphinx versions
+master_doc = root_doc
+
+# -- HTML output -------------------------------------------------------------
+
+html_theme = "sphinx_rtd_theme"
+
+html_static_path = ["_static"]
+
diff --git a/documentation/index.rst b/documentation/index.rst
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index 00000000..5abef772
--- /dev/null
+++ b/documentation/index.rst
@@ -0,0 +1,18 @@
+TESK documentation
+==================
+
+TESK (Task Execution Service for Kubernetes) provides a GA4GH-compliant
+Task Execution Service implementation designed to run on Kubernetes.
+
+This documentation describes the architecture, deployment, and integration
+options for TESK.
+
+.. toctree::
+   :maxdepth: 2
+   :caption: Contents
+
+   tesintro
+   deployment
+   integrated_wes_tes
+   local_ftp
+
diff --git a/documentation/requirements.txt b/documentation/requirements.txt
new file mode 100644
index 00000000..45c2034a
--- /dev/null
+++ b/documentation/requirements.txt
@@ -0,0 +1,4 @@
+sphinx
+sphinx-rtd-theme
+myst-parser
+